Investigation into conolidine has led to discovery of the opioid receptor in your body called ACKR3/CXCR7. ACKR3 is apparently one of the most desired focus on for conolidine, which also disregards another 4 classical opioid receptors(3). There's interest in working with conolidine like a pain-reliever based on evidence from https://bookmarksystem.com/story20678555/what-does-alternative-natural-pain-relief-to-replace-traditional-painkillers-mean