This study aimed to assess the predictive performance of first- and second-order regression models in optimizing bedaquiline (BQ) solid lipid nanoparticle (SLN) formulations. A three-step central composite design and graphical optimization process was employed. A design of experiments method was used to evaluate the impact of BQ. Tween 80 (T80). https://www.alarecre.com/Disney-The-Nightmare-Before-Christmas-Lock-Shock-and-Barrel-Art-AirPods-Pro-2nd-Gen-Skin-p101716/