Rectal foam or suppositories to treat ulcerative colitis (proctitis) or for Crohn's disease affecting the rectum. An acute exacerbation is more commonly known as a 'flare-up'. An acute exacerbation of chronic obstructive pulmonary disease (COPD) is a sudden worsening of COPD symptoms compared with the usual severity of symptoms. Topical https://escatter11.fullerton.edu/nfs/show_user.php?userid=7325677