Nicotine dependence is when One's body will get used to nicotine and the sensations it creates. Substance use problem (SUD) is when Your entire body needs nicotine to stop withdrawal symptoms. Mainly because nicotine disturbs your brain’s reward circuits, it’s hugely addictive. Infertility and impotence. Smoking cigarettes boosts the hazard https://www.patreon.com/Icyshop